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Expression of c-KIT and its ligand, stem cell factor, in normal and subfertile human testicular tissue
Germ cells proto-oncogenes testis stem cells
2009/2/16
The c-KIT proto-oncogene encodes for a transmembrane receptor and is associated with maturation of several cell types, including germ cells. The ligand of the receptor has been identified as stem ...
Transmembrane versus soluble stem cell factor expression in human testis
Transmembrane soluble stem cell human testis
2008/12/25
The interaction between stem cell factor (SCF), a ligand produced by Sertoli cells, and its c-kit receptor on germ cells is necessary for successful spermatogenesis in animal models. SCF can be alte...