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Synthesis and Structure-Activity Relationships of Dinotefuran Derivatives：Modification in the Tetrahydro-3-furylmethyl Part
neonicotinoids (±)-tetrahydro-3-furylmethyl dinotefuran acetylcholine structure-activity relationships (SAR)
2009/3/7
The (±)-tetrahydro-3-furylmethyl moiety, which is a characteristic part of the novel neonicotinoid dinotefuran, was found by research in which acetylcholine was selected as the lead compound. SAR (s...
Synthesis and Structure-Activity Relationships of Dinotefuran Derivatives: Modification in the Nitroguanidine Part
dinotefuran neonicotinoids (±)-tetrahydro-3-furylmethyl structure-activity relationships (SAR)
2009/3/7
Dinotefuran ((RS)-1-methyl-2-nitro-3-(tetrahydro-3-furylmethyl)guanidine) is a new neonicotinoid which has a characteristic (±)-tetrahydro-3-furylmethyl moiety instead of the pyridine-like moiety of...
Structure–activity relationships and pathway analysis of biological degradation processes
structure–activity relationships pathway analysis biodegradation 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane
2009/3/5
(Q)SARs estimate biological activity; however these models are insufficient to fully understand and predict the ADME-Tox processes of small molecules in biological systems. By integrating (Q)SARs wi...
Quantitative structure–activity relationships of imidacloprid and its analogs with substituents at the C5 position on the pyridine ring in the neuroblocking activity
imidacloprid analogs QSAR neuroblocking activity radioligand
2009/3/5
Two nerve activities of imidacloprid analogs with various substituents at the 5-position of the pyridine ring were measured: the conduction blockage in the excised central nerve cord of the American...
Actions of imidacloprid, clothianidin and related neonicotinoids on nicotinic acetylcholine receptors of American cockroach neurons and their relationships with insecticidal potency
imidacloprid clothianidin neonicotinoids nicotinic acetylcholine receptors
2009/3/5
The actions of neonicotinoid insecticides on nicotinic acetylcholine receptors (nAChRs) in the terminal abdominal ganglion neurons of the American cockroach were investigated using whole-cell patch-...