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A Novel Network Biology Approach To Drug Target Selections
Network Biology Approach Drug Target Selections
2015/5/26
Conventional drug discovery focuses on single protein targets and follows a “sequence,
structure, and function” paradigm for selecting best protein targets to screen lead
chemical compounds. This es...
A Novel Approach For Stable, Cell-Type Restricted Knockdown of Gene Expression in C.ELEGANS
Biological sciences Cell-type restricted knockdown Gene expression C. elegans
2014/12/10
Removal of protein activity by genetic mutation or pharmacological inhibition has been used extensively to understand the normal function of a protein. However, null mutations eliminate gene function ...
A PhD student from CSIRO and The University of Queensland has found a better way to 'spell check' gene sequences and help biologists better understand the natural world.
期刊信息
篇名
A new approach for rapidly reshaping single-chain antibody in vitro bycombining DNA shuffling with ribosome display.
语种
英文
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作者
Wang XB,Zhou B,Yin CC,Lin Q,Huang HL
第一作者单位
刊物名称
J Biochem (...
期刊信息
篇名
Phylogeny of prokaryotes and chloroplasts revealed by a simple composition approach on all protein sequences from whole genome without sequence alignment
语种
英文
撰写或编译
撰写
作者
Z.G. Yu,L.Q. Zhou,V...