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An IL-4-dependent macrophage-iNKT cell circuit resolves sterile inflammation and is defective in mice with chronic granulomatous disease
macrophage-iNKT cel chronic granulomatous disease
2015/5/21
The immune system initiates tissue repair following injury. In response to sterile tissue injury, neutrophils infiltrate the tissue to remove tissue debris and subsequently undergo apoptosis. Proper c...
Control of inflammation, helper T cell responses and regulatory T cell function by Bcl6
cells microRNAs eosinophilic esophagitis asthma
2015/5/21
Regulatory T (Treg) cells represent an important layer of immune-regulation indispensible for curtailing exuberant inflammatory responses and maintaining self-tolerance. Treg cells have translational ...
PAK1's regulation of eosinophil migration and implications for asthmatic inflammation
airway inflammation p-21 activated kinase 1 (PAK1) chemotaxis
2015/5/21
More than 300 million people world-wide suffer from breathlessness, wheezing, chest tightness, and coughing characteristic of chronic bronchial asthma, the global incidence of which is on the rise. Al...