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Development and time-course of bleomycin-induced pulmonary fibrosis in NMRI mice
Pulmonary fibrosis NMRI mice
2010/4/7
Bleomycin-induced pulmonary fibrosis is a widely used experimental model for human lung fibrosis. The severity of fibrosis varies among different strains of mice and investigation on different strains...
The effect of AT1 receptor blockade on bax and bcl-2 expression in bleomycin-induced pulmonary fibrosis
bcl-2 bax bleomycin pulmonary fibrosis losartan
2009/12/14
ABSTRACT
Background and the purpose of the study: Recent studies have indicated the role of apoptosis and angiotensin in the pathogenesis of bleomycin induced-pulmonary fibrosis. Losartan, an angiote...
Vitamin A Derivative Etretinate Improves Bleomycin-induced Scleroderma
apoptosis bleomycin collagen etretinate scleroderma
2010/11/22
There was a significant decrease in mean dermal thickness (P < 0.05) and changes in collagen bundles in the etretinate-treated mice group for a 28-day period compared to control groups. TUNEL assay sh...