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Leucine supplementation enhances integrative myofibrillar protein synthesis in free-living older men consuming lower- and higher-protein diets: a parallel-group crossover study
aging deuterated water dietary protein leucine muscle protein synthesis
2018/12/19
Background: Leucine co-ingestion with lower-protein (LP)–containing meals may overcome the blunted muscle protein synthetic response to food intake in the elderly but may be effective only in individu...
Effects of calcium supplementation on body weight: a meta-analysis
body weight calcium meta-analysis obesity body mass index
2018/12/18
Background: Whether calcium supplementation can reduce body weight and prevent obesity remains unclear because of inconsistent reports.
Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development
birth defects developmental defects embryo folic acid high folate methylenetetrahydrofolate reductase MTHFD1 placenta
2018/12/19
Background: Moderately high folic acid intake in pregnant women has led to concerns about deleterious effects on the mother and fetus. Common polymorphisms in folate genes, such as methylenetetrahydro...
Effects of prenatal multiple micronutrient supplementation on growth and cognition through 2 y of age in rural Bangladesh: the JiVitA-3 Trial
micronutrients prenatal children growth stunting cognition
2018/12/14
Background: Childhood undernutrition may have prenatal origins, and the impact of prenatal interventions on postnatal growth is not well known.
Hypercalcemia, hypercalciuria, and kidney stones in long-term studies of vitamin D supplementation: a systematic review and meta-analysis
hypercalcemia hypercalciuria kidney stones randomized controlled trials vitamin D supplements
2018/12/14
Background: Vitamin D supplementation is increasingly being used in higher doses in randomized controlled trials (RCTs). However, adverse events from very large annual doses of vitamin D have been sho...
Effects of prenatal multiple micronutrient supplementation on growth and cognition through 2 y of age in rural Bangladesh: the JiVitA-3 Trial
micronutrients prenatal children growth stunting cognition
2018/12/18
Background: Childhood undernutrition may have prenatal origins, and the impact of prenatal interventions on postnatal growth is not well known.
Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial
insulin sensitivity mitochondrial capacity obesity polyphenols resveratrol
2018/12/3
Background: The obese insulin-resistant state is characterized by impairments in lipid metabolism. We previously showed that 3-d supplementation of combined epigallocatechin-3-gallate and resveratrol ...
Vitamin D status of black and white Americans and changes in vitamin D metabolites after varied doses of vitamin D supplementation
vitamin D free vitamin D vitamin D-binding protein clinical trial African American white supplementation
2018/12/3
Background: Controversy exists over the disparate circulating 25-hydroxyvitamin D [25(OH)D] concentrations between black and white Americans.
Effect of ω-3 supplementation on placental lipid metabolism in overweight and obese women
lipid metabolism ω-3 fatty acids placenta pregnancy obesity
2018/11/29
Background: The placentas of obese women accumulate lipids that may alter fetal lipid exposure. The long-chain omega-3 fatty acids (n–3 FAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) ...
Short children with a low midupper arm circumference respond to food supplementation: an observational study from Burkina Faso
MUAC moderate acute malnutrition stunting treatment undernutrition
2018/11/27
Background: The management of children with moderate acute malnutrition (MAM) is based on food supplementation in outpatient programs. When midupper arm circumference (MUAC) is used as the sole admiss...
Impact of a 6-wk olive oil supplementation in healthy adults on urinary proteomic biomarkers of coronary artery disease, chronic kidney disease, and diabetes (types 1 and 2): a randomized, parallel, controlled, double-blind study
Mediterranean diet coronary artery disease olive oil phenolics proteomic biomarkers
2018/12/19
Background: Olive oil (OO) consumption is associated with cardiovascular disease prevention because of both its oleic acid and phenolic contents. The capacity of OO phenolics to protect against low-de...
The Regulation and Expression of the Creatine Transporter: A Brief Review of Creatine Supplementation in Humans and Animals
creatine monohydrate sports supplements ergogenic aids
2015/3/13
Creatine monohydrate has become one of the most popular ergogenic sport supplements used
today. It is a nonessential dietary compound that is both endogenously synthesized and naturally
ingested t...